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Armoring CAR T cells to take on cancer
 3D visualization showing a reddish-blue tumor mass with internal vasculature, surrounded by blue CAR T cells and small extracellular vesicles against a dark background.

Armoring CAR T cells to take on cancer

Researchers from across Penn collaborated to discover how solid tumors communicate with engineered cancer-fighting cells causing them to commit fratricide and inhibit treatment. Their findings point toward improved therapies for treating cancers.

3 min. read

https://in-principle-and-practice.upenn.edu/
Students walk beneath The Covenant on Locust Walk at dusk

In Principle and Practice

Penn’s strategic framework

Penn’s guiding principles are the University’s enduring values and distinctive strengths: anchored, inventive, interwoven, and engaged. The practices support and strengthen Penn’s core educational mission. 

At 今天潘, we focus on some of the ways the University is putting this framework into action. From student, faculty, and staff profiles to research updates and event coverage, 今天潘 highlights the latest examples of the University’s principled approach to excellence.

Penn lends support to Rebuilding Together Philadelphia effort repairing 11 local homes in two days
Volunteers smiling and carrying tools and supplies during the block build event.

Penn lends support to Rebuilding Together Philadelphia effort repairing 11 local homes in two days

Marking a milestone block build, 70 Penn volunteers combined forces with Rebuilding Together Philadelphia, a nonprofit with roots at the University, to revitalize owner-occupied houses in the West Philadelphia community. The momentous two-day event involved a block build and speaking program—with a local homeowner sharing a heartfelt message.

2 min. read

Evaluating large language models for cyberbullying behavior
A portrait of Helen Jin at Amy Gutmann Hall.

Evaluating large language models for cyberbullying behavior

In the Brachio Lab, doctoral students at Penn Engineering probe AI models for signs of cyberbullying capabilities. This emerging problem with the rise of AI may pose challenges in areas like business, education, and public health.

5 min. read

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